Although usually harmless to you and your baby, it really is painful and leave you feeling uncomfortable. There are several simple steps you can take should you be pregnant and suffering from heartburn or indigestion. Sodium alginate forms a gel-like layer on top of the acid in the stomach.
Although the formal efficacy study was completed over 4 weeks, the protocol allowed women to continue LG use through pregnancy if they wished, and thus the safety study was completed with long-term real-life use. The study was completed in the UK and South Africa, and adverse events for the mother, fetus, and baby were in keeping with the populace norms for those countries.
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Adverse events and fetal/neonatal deaths were in keeping with the populace incidences in the UK and South Africa (Table 3) and indicated no safety concerns for LG use during pregnancy. It ought to be noted that the infant mortality rate (perinatal and neonatal) in South Africa is variable according to the socioeconomic status [22, 23]. Caesarean section rates are high in South Africa, but as the study group contains some private clinics, the rate of Caesarean section is estimated to be 30%. Treatment of GER in pregnancy obviously should be conservative, and a step-up approach is advocated.
July 2011 – minor update. Text changed in line with the UKMi (UK Medicines information) publication regarding choice of proton pump inhibitors for the treatment of reflux in women that are breastfeeding.
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Be mindful of one’s posture and keep your back straight when you are eating and for another half an hour afterwards. This can be a straightforward and easy way to help avoid indigestion when you are pregnant as sitting in this position will need pressure off of your stomach – for as long, needless to say, as this is comfortable for you personally and you have sufficient support for the back.
This study used a typical real-life dosage regimen for the reason that patients could take medication as required (up to a maximum of 80â€‰mL each day). Although the formal efficacy study lasted for 4 weeks, the protocol allowed patients to continue treatment if desired (which the majority did), thus this more accurately reflected normal clinical practice and allowed assessment of longer term safety of the medication rather than a fixed short-term study. Interestingly, when symptom frequency and severity were broken down by daytime or nighttime, it had been shown that heartburn was classified most often as severe during the night but only moderate throughout the day in pregnant women. At baseline, 51% of women documented severe or very severe nocturnal heartburn which was reduced to 32% after four weeks of treatment.
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Alginate-based reflux suppressant was assigned to the treatment group and magnesium-aluminium antacid gel to the control group. Drug dose was 15â€‰ml oral three times after meal and before bedtime. Treatment was continued for just two 2 weeks. Treatment assignment had not been revealed until data collection was completed.
Drug interactions may change how your medications work or boost your risk for serious side effects. This document will not contain all possible drug interactions. Keep a listing of all of the products you use (including prescription/nonprescription drugs and herbal products) and share it together with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval. During pregnancy, this medication ought to be used only once clearly needed.
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The bottom line is that, if heartburn during pregnancy is something you canâ€™t manage or prevent together with your diet, itâ€™s easier to try a combination of treatments, versus taking too much of one thing. So, why arenâ€™t there warnings about unwanted effects?
Addititionally there is evidence suggesting that pre-pregnancy heartburn and weight gain during pregnancy increase the threat of heartburn during pregnancy ( Rey et al 2007 ) . Lifestyle changes such as stress reduction programs, stopping smoking, limiting alcohol, and diet changes (e.g., avoiding caffeine, fatty foods, certain spices) may raise the effectiveness of this medication. Talk to your doctor or pharmacist about changes in lifestyle that may benefit you.