Along with developing X-ray microscopes, Gerd Schneider’s workgroup has contributed tremendously to the improvement of the lenses, known as Fresnel area plates. Given such 3D X-ray lenses and modern day synchrotron sources like BESSY II, great contributions could be manufactured towards answering countless scientific queries, from the basics of structural biology to analyze into modern energy storage solutions. We developed a new full-field transmitting X-ray microscope (TXM) for automated cryo-tomography and spectroscopy. The system works at the BESSY undulator U41 at a concentrating spherical grating monochromator beamline, which provides a power resolution up to 104.
Even chemical substance bonding states could be clearly imaged employing near-edge spectroscopy. Because the factors exhibit characteristic fluorescence under X-ray lamps, you can also clearly ascertain the spatial distribution of extremely very low concentrations of elements in an example. In this way, X-ray microscopy offers a thorough picture of each sample. The workgroup of Gerd Schneider functions probably the most advanced X-ray microscopes in the world, that allows spatial resolutions of down to ten nanometres using the “soft” X-ray light source from BESSY II. Dr. Schneider offers been my medical doctor since i have first arrived in Ottawa in 1976 (41years).
Experts at Helmholtz-Zentrum Berlin (HZB) are suffering from a new X-ray nanotomography microscope. Using their new system, they can reveal the structures on the tiniest components of mammalian cells in three measurements. For the very first time, you don’t have to chemically fix, stain or lower cells in order to study them.
Dr Schneider is one of the nicest & most caring doctors I have ever had. Dr Schneider was basically extremely pleasant and specialized. She carefully examined the issue and devised a sensible plan to move forward.
In the talk, we present the new TXM and selected applications. The transmitting X-ray microscope’s 3D PSF exhibits an axial asymmetry that cannot be described by an incoherent imaging unit for either a lens or zone plate, with or without spherical aberration.
Glenn T. Schneider, M.D., M.S.
“I became a health care provider because I love the mental concern of thinking by way of a problem to be able to find a solution to help someone,” claims Dr. Schneider. His patients identify him as caring, sort, compassionate, and full of energy. He places an focus on family, as an integral portion of the community, and supplying high-quality good care and optimal surgical technique. Researchers achieved this large 3-D image resolution by illuminating when structures of the frozen-hydrated item with partially coherent light source. This lighting is developed by BESSY II, the synchrotron supply at HZB.
Partial coherence may be the property of two waves whose relative period undergoes random fluctuations which are not, however, sufficient to make the wave completely incoherent. Illumination with partial coherent light source generates significantly bigger contrast for smaller object details in comparison to incoherent illumination. Combining this process with a high-resolution zoom lens, the researchers were able to visualize the ultrastructures of tissue at hitherto unattained contrast. Slice through the nucleus of a mouse adenocarcinoma cell displaying the nucleolus (NU) and the membrane channels running over the nucleus (NMC); consumed by X-ray nanotomography.
The professorship is associated with heading the workgroup “X-ray microscopy” at the Helmholtz-Zentrum Berlin für Materialien und Energie. With his party, the internationally recognised specialist is developing innovative methods and programs for X-ray microscopy, which delivers essential information for most scientific disciplines – from material and strength research to the life span sciences.